[Malformation syndromes associated with childhood cancer: an update]. / Anomalies de développement et prédisposition aux tumeurs de l'enfant.
Arch Pediatr
; 17(8): 1220-7, 2010 Aug.
Article
in Fr
| MEDLINE
| ID: mdl-20598868
ABSTRACT
Biology, genetics and environment of childhood solid tumours set them apart from adult solid tumours. The nature of the progenitor cells from which these tumours arise, and their immature tissue environment, allows childhood solid tumours to develop with fewer defects in cell regulatory processes. Constitutional molecular defects are known to play a role in childhood solid tumours, as shown by the increased incidence of embryonic cancers in children carrying malformations associated with childhood cancer. These rare diagnoses are commonly missed. In this article, we reviewed the spectrum of these tumour predisposition syndromes.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chromosome Aberrations
/
Neoplasms
Type of study:
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Child
/
Humans
Language:
Fr
Journal:
Arch Pediatr
Year:
2010
Document type:
Article
Affiliation country:
France