Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells.

Yang, H; Wang, Z; Capó-Aponte, J E; Zhang, F; Pan, Z; Reinach, P S

Yang, H; Wang, Z; Capó-Aponte, J E; Zhang, F; Pan, Z; Reinach, P S.

Affiliation

Yang H; Department of Biological Sciences, State University of New York, State College of Optometry, New York, NY 10036, USA.

Exp Eye Res ; 91(3): 462-71, 2010 Sep.

Article in En | MEDLINE | ID: mdl-20619260

Subject(s)

Epithelium, Corneal/metabolism; ErbB Receptors/metabolism; Receptor, Cannabinoid, CB1/metabolism; TRPV Cation Channels/metabolism; Transcriptional Activation/physiology; Benzoxazines/pharmacology; Blotting, Western; Capsaicin/pharmacology; Cell Movement; Cell Proliferation; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal/drug effects; ErbB Receptors/antagonists & inhibitors; Fluorescent Antibody Technique, Indirect; Humans; Interleukin-6/metabolism; Interleukin-8/metabolism; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/metabolism; Mitogen-Activated Protein Kinase 8/metabolism; Mitogen-Activated Protein Kinase 9/metabolism; Morpholines/pharmacology; Naphthalenes/pharmacology; Phosphorylation; Piperidines/pharmacology; Pyrazoles/pharmacology; Quinazolines; Receptor, Cannabinoid, CB1/antagonists & inhibitors; TRPV Cation Channels/antagonists & inhibitors; Tyrphostins/pharmacology; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcriptional Activation / Epithelium, Corneal / Receptor, Cannabinoid, CB1 / TRPV Cation Channels / ErbB Receptors Limits: Humans Language: En Journal: Exp Eye Res Year: 2010 Document type: Article Affiliation country: United States Country of publication: United kingdom

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