Statistical optimization of process variables for the production of an anticancer drug (colchicine derivatives) through fermentation: at scale-up level.

Dubey, Kashyap Kumar; Behera, B K

Dubey, Kashyap Kumar; Behera, B K.

Affiliation

Dubey KK; Industrial Biotech Laboratory, University Institute of Engineering and Technology, M.D. University Rohtak-124001, Haryana, India.

N Biotechnol ; 28(1): 79-85, 2011 Jan 31.

Article in En | MEDLINE | ID: mdl-20647066

Subject(s)

Antineoplastic Agents/chemical synthesis; Biotechnology/methods; Colchicine/analogs & derivatives; Colchicine/biosynthesis; Fermentation; Models, Statistical; Aerobiosis; Antineoplastic Agents/chemistry; Bacillus megaterium/metabolism; Bioreactors/microbiology; Biotransformation; Colchicine/chemistry; Hydrogen-Ion Concentration; Methylation; Reproducibility of Results; Temperature

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biotechnology / Colchicine / Models, Statistical / Fermentation / Antineoplastic Agents Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: N Biotechnol Journal subject: BIOLOGIA MOLECULAR / ENGENHARIA BIOMEDICA Year: 2011 Document type: Article Affiliation country: India

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