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Acute promyelocytic leukemia in Crohn's disease. Case report and review of the literature.
Orii, S; Sugai, T; Nakano, O; Yoshinari, H; Sato, S.
Affiliation
  • Orii S; First Department of Internal Medicine, School of Medicine, Iwate Medical University, Morioka, Japan.
J Clin Gastroenterol ; 13(3): 325-7, 1991 Jun.
Article in En | MEDLINE | ID: mdl-2066549
ABSTRACT
A 19-year-old man with a documented 2-year history of Crohn's disease abruptly developed leukopenia and thrombocytopenia. A diagnosis of acute promyelocytic leukemia was established by bone marrow cytology. Chromosomal analysis of bone marrow aspirate revealed aberrations of no. 8 trisomy and translocation between no. 15 and no. 17 [46,XY,t(15q+,17q-)/47,XY,+8,t(15q+,17q-)]. Nine cases of Crohn's disease complicated by leukemia have been reported, including the present one; once again, a relationship between Crohn's disease and leukemia is suggested.
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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Promyelocytic, Acute / Crohn Disease / Chromosome Aberrations Limits: Adult / Humans / Male Language: En Journal: J Clin Gastroenterol Year: 1991 Document type: Article Affiliation country: Japan
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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Promyelocytic, Acute / Crohn Disease / Chromosome Aberrations Limits: Adult / Humans / Male Language: En Journal: J Clin Gastroenterol Year: 1991 Document type: Article Affiliation country: Japan