Comparison of cyclooxygenase-1 crystal structures: cross-talk between monomers comprising cyclooxygenase-1 homodimers.

Sidhu, Ranjinder S; Lee, Jullia Y; Yuan, Chong; Smith, William L

Sidhu, Ranjinder S; Lee, Jullia Y; Yuan, Chong; Smith, William L.

Affiliation

Sidhu RS; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

Biochemistry ; 49(33): 7069-79, 2010 Aug 24.

Article in En | MEDLINE | ID: mdl-20669977

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/chemistry; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Cyclooxygenase 1/chemistry; Cyclooxygenase 1/metabolism; Cyclooxygenase 2 Inhibitors/chemistry; Cyclooxygenase 2 Inhibitors/pharmacology; Animals; Aspirin/chemistry; Aspirin/pharmacology; Catalytic Domain; Crystallography, X-Ray; Diclofenac/chemistry; Diclofenac/pharmacology; Flurbiprofen/chemistry; Flurbiprofen/pharmacology; Ligands; Models, Molecular; Protein Binding; Protein Conformation; Protein Multimerization; Sheep; Sulfonamides/chemistry; Sulfonamides/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Inflammatory Agents, Non-Steroidal / Cyclooxygenase 1 / Cyclooxygenase 2 Inhibitors Limits: Animals Language: En Journal: Biochemistry Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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