Spray-dried doxorubicin-albumin microparticulate systems for treatment of multidrug resistant melanomas.

Jones, Alphia K; Bejugam, Naveen K; Nettey, Henry; Addo, Richard; D'Souza, Martin J

Jones, Alphia K; Bejugam, Naveen K; Nettey, Henry; Addo, Richard; D'Souza, Martin J.

Affiliation

Jones AK; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Mercer University, Atlanta, GA, USA. kjon74@aol.com

J Drug Target ; 19(6): 427-33, 2011 Jul.

Article in En | MEDLINE | ID: mdl-20678033

Subject(s)

Antibiotics, Antineoplastic/therapeutic use; Doxorubicin/therapeutic use; Drug Resistance, Multiple/drug effects; Drug Resistance, Neoplasm/drug effects; Melanoma/drug therapy; Serum Albumin, Bovine/therapeutic use; Animals; Antibiotics, Antineoplastic/administration & dosage; Antibiotics, Antineoplastic/chemistry; Antibiotics, Antineoplastic/pharmacokinetics; Cell Line, Tumor; Cell Survival/drug effects; Doxorubicin/administration & dosage; Doxorubicin/chemistry; Doxorubicin/pharmacokinetics; Drug Compounding/methods; Mice; Microspheres; Particle Size; Rats; Serum Albumin, Bovine/administration & dosage; Serum Albumin, Bovine/chemistry; Serum Albumin, Bovine/pharmacokinetics; Solubility; Surface Properties

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serum Albumin, Bovine / Doxorubicin / Drug Resistance, Multiple / Drug Resistance, Neoplasm / Melanoma / Antibiotics, Antineoplastic Limits: Animals Language: En Journal: J Drug Target Journal subject: FARMACOLOGIA Year: 2011 Document type: Article Affiliation country: United States

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