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A brief introduction to RNAi and microRNAs in stem cells.
Murashov, Alexander K.
Affiliation
  • Murashov AK; Department of Physiology, East Carolina University, School of Medicine, Greenville, NC, USA.
Methods Mol Biol ; 650: 15-25, 2010.
Article in En | MEDLINE | ID: mdl-20686940
ABSTRACT
Recently, RNAi, including microRNAs (miRNAs), has become an important tool to investigate the regulatory mechanism of stem cell maintenance and differentiation. In this short chapter, we will give a brief overview of the discovery history, functions, and mechanisms of RNAi and miRNAs. We will also discuss RNAi as a tool to study stem cell function and the potential future practical applications.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / MicroRNAs / RNA Interference Limits: Animals / Humans Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2010 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / MicroRNAs / RNA Interference Limits: Animals / Humans Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2010 Document type: Article Affiliation country: United States