The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers.

Zhang, Yu; Gostissa, Monica; Hildebrand, Dominic G; Becker, Michael S; Boboila, Cristian; Chiarle, Roberto; Lewis, Susanna; Alt, Frederick W

Zhang, Yu; Gostissa, Monica; Hildebrand, Dominic G; Becker, Michael S; Boboila, Cristian; Chiarle, Roberto; Lewis, Susanna; Alt, Frederick W.

Affiliation

Zhang Y; Howard Hughes Medical Institute, Boston, Massachusetts, USA.

Adv Immunol ; 106: 93-133, 2010.

Article in En | MEDLINE | ID: mdl-20728025

Subject(s)

Neoplasms/genetics; Translocation, Genetic; Animals; B-Lymphocytes/physiology; Chromosome Breakage; DNA Breaks, Double-Stranded; DNA Repair; Gene Expression Regulation, Neoplastic; Genes, RAG-1; Humans; Immunoglobulin Class Switching; Leukemia/genetics; Lymphoma/genetics; Philadelphia Chromosome; Recombination, Genetic; Regulatory Sequences, Nucleic Acid; T-Lymphocytes/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Translocation, Genetic / Neoplasms Type of study: Guideline / Prognostic_studies Limits: Animals / Humans Language: En Journal: Adv Immunol Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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