TLR2-mediated expansion of MDSCs is dependent on the source of tumor exosomes.

Xiang, Xiaoyu; Liu, Yuelong; Zhuang, Xiaoyin; Zhang, Shuangqin; Michalek, Sue; Taylor, Douglas D; Grizzle, William; Zhang, Huang-Ge

Xiang, Xiaoyu; Liu, Yuelong; Zhuang, Xiaoyin; Zhang, Shuangqin; Michalek, Sue; Taylor, Douglas D; Grizzle, William; Zhang, Huang-Ge.

Affiliation

Xiang X; Department of Microbiology & Immunology, JamesBrown Cancer Center, University of Louisville, Louisville, Kentucky 40202, USA.

Am J Pathol ; 177(4): 1606-10, 2010 Oct.

Article in En | MEDLINE | ID: mdl-20802178

Subject(s)

Exosomes/metabolism; Interleukin-6/metabolism; Lymphoma/metabolism; Mammary Neoplasms, Experimental/metabolism; Melanoma, Experimental/metabolism; Myeloid Cells/metabolism; Toll-Like Receptor 2/metabolism; Animals; Blotting, Western; Cells, Cultured; Coculture Techniques; Enzyme-Linked Immunosorbent Assay; Lymphoma/pathology; Mammary Neoplasms, Experimental/pathology; Melanoma, Experimental/pathology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cells/cytology; Myeloid Differentiation Factor 88/metabolism; Spleen/cytology; Spleen/metabolism; T-Lymphocytes/metabolism; Tumor Microenvironment

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Melanoma, Experimental / Interleukin-6 / Myeloid Cells / Toll-Like Receptor 2 / Exosomes / Lymphoma / Mammary Neoplasms, Experimental Limits: Animals Language: En Journal: Am J Pathol Year: 2010 Document type: Article Affiliation country: United States

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