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Original and efficient synthesis of D-cycloserine.
Li, Xiaomeng; Meng, Xia; Duan, Hongdong; Wang, Lizhen; Wang, Shixiao; Zhang, Yi; Qin, Dawei.
Affiliation
  • Li X; School of Chemical Engineering, Shandong Institute of Light Industry, Jinan, PR China.
Arch Pharm (Weinheim) ; 343(8): 473-5, 2010 Aug.
Article in En | MEDLINE | ID: mdl-20803624
A simple pathway for the preparation of D-cycloserine is presented. The intermediates and D-cycloserine were characterized by FT-IR, (1)H-NMR spectra and elemental analysis. D-Cycloserine can inhibit the growth of Mycobacterium tuberculosis and can be used as a second-line drug for the treatment of tuberculosis, especially for the use in developing countries.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / Cycloserine / Mycobacterium tuberculosis Limits: Humans Language: En Journal: Arch Pharm (Weinheim) Year: 2010 Document type: Article Country of publication: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / Cycloserine / Mycobacterium tuberculosis Limits: Humans Language: En Journal: Arch Pharm (Weinheim) Year: 2010 Document type: Article Country of publication: Germany