ß-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.

Ahmad, I; Morton, J P; Singh, L B; Radulescu, S M; Ridgway, R A; Patel, S; Woodgett, J; Winton, D J; Taketo, M M; Wu, X-R; Leung, H Y; Sansom, O J

Ahmad, I; Morton, J P; Singh, L B; Radulescu, S M; Ridgway, R A; Patel, S; Woodgett, J; Winton, D J; Taketo, M M; Wu, X-R; Leung, H Y; Sansom, O J.

Affiliation

Ahmad I; The Beatson Institute for Cancer Research, Glasgow, Scotland, UK.

Oncogene ; 30(2): 178-89, 2011 Jan 13.

Article in En | MEDLINE | ID: mdl-20818428

Subject(s)

Carcinoma, Papillary/metabolism; Cell Transformation, Neoplastic/metabolism; PTEN Phosphohydrolase/metabolism; Urinary Bladder Neoplasms/chemically induced; beta Catenin/metabolism; Adenomatous Polyposis Coli Protein/genetics; Animals; Cell Proliferation; Cohort Studies; Female; Humans; Hyperplasia/chemically induced; Male; Mice; Phosphatidylinositol 3-Kinases/metabolism; Proto-Oncogene Proteins c-akt/analysis; Proto-Oncogene Proteins c-akt/metabolism; Sequence Deletion; TOR Serine-Threonine Kinases/metabolism; Urinary Bladder/metabolism; Urothelium/metabolism; Wnt Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Carcinoma, Papillary / Cell Transformation, Neoplastic / PTEN Phosphohydrolase / Beta Catenin Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2011 Document type: Article Affiliation country: United kingdom

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