Photoaging: the role of oxidative stress.
G Ital Dermatol Venereol
; 145(4): 445-59, 2010 Aug.
Article
in En
| MEDLINE
| ID: mdl-20823789
ABSTRACT
Our skin suffers from daily exposure to oxidative stress, primarily from exposure to the sun's damaging ultraviolet (UV) rays. This results in the appearance of premature aging. The mechanisms of this photodamage to all layers of the skin by the various wavelengths (UVB and UVA) will be clarified. Recent research further demonstrates a synergistic enhancement of oxidative damage when the skin is exposed to UVA in combination with environmental urban pollutants (including cigarette smoke). The fact that photoaging is largely caused by oxidative damage is confirmed by the demonstration that treatment with topical antioxidants can prevent and even partially reverse UV-induced photodamage. Research substantiating the efficacy of vitamins C and E and of selenium will be reviewed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin Aging
/
Oxidative Stress
Limits:
Humans
Language:
En
Journal:
G Ital Dermatol Venereol
Year:
2010
Document type:
Article
Affiliation country:
United States