Your browser doesn't support javascript.
loading
Genetic analysis of mobile tetQ elements in oral Prevotella species.
Tribble, Gena D; Garza, John J; Yeung, Victor L; Rigney, Todd W; Dao, Doan-Hieu V; Rodrigues, Paulo H; Walker, Clay B; Smith, Charles J.
Affiliation
  • Tribble GD; Department of Periodontics, University of Texas Health Science Center at Houston, 77030, USA. gena.d.tribble@uth.tmc.edu
Anaerobe ; 16(6): 604-9, 2010 Dec.
Article in En | MEDLINE | ID: mdl-20826220
Prevotella species are members of the bacterial oral flora and are opportunistic pathogens in polymicrobial infections of soft tissues. Antibiotic resistance to tetracyclines is common in these bacteria, and the gene encoding this resistance has been previously identified as tetQ. The tetQ gene is also found on conjugative transposons in the intestinal Bacteroides species; whether these related bacteria have transmitted tetQ to Prevotella is unknown. In this study, we describe our genetic analysis of mobile tetQ elements in oral Prevotella species. Our results indicate that the mobile elements encoding tetQ in oral species are distinct from those found in the Bacteroides. The intestinal bacteria may act as a reservoir for the tetQ gene, but Prevotella has incorporated this gene into an IS21-family transposon. This transposon is present in Prevotella species from more than one geographical location, implying that the mechanism of tetQ spread between oral Prevotella species is highly conserved.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tetracycline Resistance / Prevotella / Interspersed Repetitive Sequences / Genes, Bacterial / Mouth Limits: Humans Language: En Journal: Anaerobe Year: 2010 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tetracycline Resistance / Prevotella / Interspersed Repetitive Sequences / Genes, Bacterial / Mouth Limits: Humans Language: En Journal: Anaerobe Year: 2010 Document type: Article Affiliation country: United States Country of publication: United kingdom