The oxysterol 27-hydroxycholesterol increases ß-amyloid and oxidative stress in retinal pigment epithelial cells.

Dasari, Bhanu; Prasanthi, Jaya R P; Marwarha, Gurdeep; Singh, Brij B; Ghribi, Othman

Dasari, Bhanu; Prasanthi, Jaya R P; Marwarha, Gurdeep; Singh, Brij B; Ghribi, Othman.

Affiliation

Dasari B; Department of Pharmacology, University of North Dakota School of Medicine and Health Sciences, 501 North Columbia Road, Grand Forks, North Dakota 58202, USA. oghribi@medicine.nodak.edu

BMC Ophthalmol ; 10: 22, 2010 Sep 13.

Article in En | MEDLINE | ID: mdl-20836858

Subject(s)

Hydroxycholesterols/pharmacology; Macular Degeneration/metabolism; Oxidative Stress/drug effects; Retinal Pigment Epithelium/metabolism; Alzheimer Disease/metabolism; Amyloid beta-Peptides/metabolism; Blotting, Western; Calcium/metabolism; Cells, Cultured; Cholesterol/metabolism; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Macular Degeneration/pathology; Microscopy, Confocal; Reactive Oxygen Species/metabolism; Retinal Pigment Epithelium/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Retinal Pigment Epithelium / Hydroxycholesterols / Macular Degeneration Limits: Humans Language: En Journal: BMC Ophthalmol Journal subject: OFTALMOLOGIA Year: 2010 Document type: Article Affiliation country: United States Country of publication: United kingdom

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