IAP inhibitors enhance co-stimulation to promote tumor immunity.

Dougan, Michael; Dougan, Stephanie; Slisz, Joanna; Firestone, Brant; Vanneman, Matthew; Draganov, Dobrin; Goyal, Girija; Li, Weibo; Neuberg, Donna; Blumberg, Richard; Hacohen, Nir; Porter, Dale; Zawel, Leigh; Dranoff, Glenn

Dougan, Michael; Dougan, Stephanie; Slisz, Joanna; Firestone, Brant; Vanneman, Matthew; Draganov, Dobrin; Goyal, Girija; Li, Weibo; Neuberg, Donna; Blumberg, Richard; Hacohen, Nir; Porter, Dale; Zawel, Leigh; Dranoff, Glenn.

Affiliation

Dougan M; Department of Medical Oncology and Cancer Vaccine Center, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

J Exp Med ; 207(10): 2195-206, 2010 Sep 27.

Article in En | MEDLINE | ID: mdl-20837698

Subject(s)

Inhibitor of Apoptosis Proteins/antagonists & inhibitors; Neoplasms/immunology; Signal Transduction; T-Lymphocytes/immunology; Animals; Antigens, Neoplasm/immunology; Cancer Vaccines; Humans; Immunomodulation; Inhibitor of Apoptosis Proteins/immunology; Inhibitor of Apoptosis Proteins/metabolism; Mice; NF-kappa B/immunology; NF-kappa B/metabolism; Neoplasms/metabolism; Tumor Necrosis Factor-alpha/immunology; Tumor Necrosis Factor-alpha/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Signal Transduction / Inhibitor of Apoptosis Proteins / Neoplasms Limits: Animals / Humans Language: En Journal: J Exp Med Year: 2010 Document type: Article Affiliation country: United States

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