Apoptosis; JNK Mitogen-Activated Protein Kinases/metabolism; Multiple Sclerosis, Relapsing-Remitting/enzymology; Signal Transduction; T-Lymphocyte Subsets/enzymology; Adult; Apoptosis/drug effects; Apoptosis/genetics; Biomarkers/metabolism; Case-Control Studies; Cells, Cultured; Cytokines/metabolism; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Humans; Inflammation Mediators/pharmacology; JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors; JNK Mitogen-Activated Protein Kinases/genetics; Lymphocyte Activation; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting/genetics; Multiple Sclerosis, Relapsing-Remitting/immunology; Multiple Sclerosis, Relapsing-Remitting/pathology; Protein Kinase Inhibitors/pharmacology; Signal Transduction/drug effects; Signal Transduction/genetics; T-Lymphocyte Subsets/drug effects; T-Lymphocyte Subsets/immunology; Young Adult