Prolonged catatonic stupor successfully treated with aripiprazole in an adolescent male with schizophrenia: a case report.
Clin Schizophr Relat Psychoses
; 4(3): 185-8, 2010 Oct.
Article
in En
| MEDLINE
| ID: mdl-20880829
ABSTRACT
We present the case of a fifteen-year-old adolescent male with schizophrenia who had long-term catatonic stupor and was successfully treated with aripiprazole. The onset of his stupor manifested rapidly after experiencing prodromal symptoms for two months. He was left untreated without adequate food ingestion for three weeks because of his parents' religious faith, and was severely dehydrated and malnourished upon admission to our hospital. After his physical recovery, treatment with risperidone (0.5-2.0 mg, 5 weeks) was started. However, hypersedation occurred, and the risperidone was switched to aripiprazole, with dose increases up to 18 mg/day (5 months). As a result, he recovered from his totally noncommunicative state. Aripiprazole, which has a unique pharmacological mechanism of action distinct from other atypical antipsychotics and an excellent safety profile, may be effective in the treatment of some schizophrenic patients with stupor, which sometimes carries a risk of physical debilitation and requires special attention due to the risk of adverse drug reactions.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Piperazines
/
Schizophrenia
/
Antipsychotic Agents
/
Catatonia
/
Quinolones
/
Stupor
Limits:
Adolescent
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
En
Journal:
Clin Schizophr Relat Psychoses
Journal subject:
PSIQUIATRIA
Year:
2010
Document type:
Article
Affiliation country:
Japan