Low molecular weight fucoidan prevents intimal hyperplasia in rat injured thoracic aorta through the modulation of matrix metalloproteinase-2 expression.

Hlawaty, Hanna; Suffee, Nadine; Sutton, Angela; Oudar, Olivier; Haddad, Oualid; Ollivier, Veronique; Laguillier-Morizot, Christelle; Gattegno, Liliane; Letourneur, Didier; Charnaux, Nathalie

Hlawaty, Hanna; Suffee, Nadine; Sutton, Angela; Oudar, Olivier; Haddad, Oualid; Ollivier, Veronique; Laguillier-Morizot, Christelle; Gattegno, Liliane; Letourneur, Didier; Charnaux, Nathalie.

Affiliation

Hlawaty H; INSERM U698, Bio-ingénierie Cardiovasculaire, Université Paris 13, France.

Biochem Pharmacol ; 81(2): 233-43, 2011 Jan 15.

Article in En | MEDLINE | ID: mdl-20887714

Subject(s)

Aorta, Thoracic/injuries; Gene Expression Regulation, Enzymologic/drug effects; Hyperplasia/prevention & control; Matrix Metalloproteinase 2/metabolism; Polysaccharides/pharmacology; Animals; Aorta, Thoracic/pathology; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Male; Matrix Metalloproteinase 2/genetics; Muscle, Smooth, Vascular/cytology; Myocytes, Smooth Muscle/drug effects; Myocytes, Smooth Muscle/physiology; Polysaccharides/chemistry; Rats; Rats, Sprague-Dawley; Tunica Intima/cytology; Tunica Intima/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aorta, Thoracic / Polysaccharides / Gene Expression Regulation, Enzymologic / Matrix Metalloproteinase 2 / Hyperplasia Limits: Animals / Humans / Male Language: En Journal: Biochem Pharmacol Year: 2011 Document type: Article Affiliation country: France Country of publication: United kingdom

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