Vascular endothelial growth factor receptor-1 signaling promotes mobilization of macrophage lineage cells from bone marrow and stimulates solid tumor growth.

Muramatsu, Masashi; Yamamoto, Seiji; Osawa, Tsuyoshi; Shibuya, Masabumi

Muramatsu, Masashi; Yamamoto, Seiji; Osawa, Tsuyoshi; Shibuya, Masabumi.

Affiliation

Muramatsu M; Department of Molecular Oncology, Graduate School of Medicine and Dentistry, Tokyo Medical and Dental University, Tokyo, Japan.

Cancer Res ; 70(20): 8211-21, 2010 Oct 15.

Article in En | MEDLINE | ID: mdl-20924106

Subject(s)

Bone Marrow Cells/physiology; Macrophages/physiology; Neoplasms/pathology; Neovascularization, Pathologic/pathology; Vascular Endothelial Growth Factor Receptor-1/physiology; Alternative Splicing; Animals; Bone Marrow Cells/pathology; Carcinoma, Lewis Lung/pathology; Cell Division; Cell Line, Tumor; DNA Primers; Female; Fibroblast Growth Factor 2/genetics; Lung Neoplasms/pathology; Macrophages/pathology; Mice; Mice, Knockout; Receptor, Fibroblast Growth Factor, Type 1/deficiency; Receptor, Fibroblast Growth Factor, Type 1/genetics; Reverse Transcriptase Polymerase Chain Reaction; Uterine Neoplasms/pathology; Vascular Endothelial Growth Factor A/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Cells / Vascular Endothelial Growth Factor Receptor-1 / Macrophages / Neoplasms / Neovascularization, Pathologic Limits: Animals Language: En Journal: Cancer Res Year: 2010 Document type: Article Affiliation country: Japan

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