Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma.

McGovern, Toby K; Powell, William S; Day, Brian J; White, Carl W; Govindaraju, Karuthapillai; Karmouty-Quintana, Harry; Lavoie, Normand; Tan, Ju Jing; Martin, James G

McGovern, Toby K; Powell, William S; Day, Brian J; White, Carl W; Govindaraju, Karuthapillai; Karmouty-Quintana, Harry; Lavoie, Normand; Tan, Ju Jing; Martin, James G.

Affiliation

McGovern TK; Meakins Christie Laboratories, Department of Medicine, McGill University, Montreal, Quebec, Canada.

Respir Res ; 11: 138, 2010 Oct 06.

Article in En | MEDLINE | ID: mdl-20925946

Subject(s)

Asthma/chemically induced; Asthma/prevention & control; Chlorine/toxicity; Irritants/toxicity; Lung/physiology; Thiourea/analogs & derivatives; Animals; Asthma/physiopathology; Chlorine/antagonists & inhibitors; Dose-Response Relationship, Drug; Inhalation Exposure/prevention & control; Irritants/antagonists & inhibitors; Lung/drug effects; Male; Mice; Mice, Inbred BALB C; Respiratory Function Tests/methods; Thiourea/therapeutic use

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Thiourea / Chlorine / Irritants / Lung Limits: Animals Language: En Journal: Respir Res Year: 2010 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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