Bioorthogonal small-molecule ligands for PARP1 imaging in living cells.

Reiner, Thomas; Earley, Sarah; Turetsky, Anna; Weissleder, Ralph

Reiner, Thomas; Earley, Sarah; Turetsky, Anna; Weissleder, Ralph.

Affiliation

Reiner T; Center for Systems Biology, Massachusetts General Hospital, Richard B. Simches Research Center, 185 Cambridge Street, Suite 5.210, Boston, MA 02114, USA.

Chembiochem ; 11(17): 2374-7, 2010 Nov 22.

Article in En | MEDLINE | ID: mdl-20967817

Subject(s)

Green Fluorescent Proteins/metabolism; Microscopy, Fluorescence/methods; Phthalazines/chemistry; Piperazines/chemistry; Poly(ADP-ribose) Polymerases/metabolism; Cell Line, Tumor; Cell Nucleus/metabolism; Cytoplasm/metabolism; Green Fluorescent Proteins/genetics; Humans; Kinetics; Ligands; Molecular Structure; Phthalazines/pharmacology; Piperazines/pharmacology; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases/genetics; Protein Transport/drug effects; Transfection; Xanthenes/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phthalazines / Piperazines / Poly(ADP-ribose) Polymerases / Green Fluorescent Proteins / Microscopy, Fluorescence Limits: Humans Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2010 Document type: Article Affiliation country: United States Country of publication: Germany

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