KRAS and BRAF mutation analysis can be reliably performed on aspirated cytological specimens of metastatic colorectal carcinoma.

Pang, N K B; Nga, M E; Chin, S Y; Ismail, T M; Lim, G L; Soong, R; Salto-Tellez, M

Pang, N K B; Nga, M E; Chin, S Y; Ismail, T M; Lim, G L; Soong, R; Salto-Tellez, M.

Affiliation

Pang NK; Divisions of Cytopathology, Department of Pathology, National University Health System, Singapore.

Cytopathology ; 22(6): 358-64, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21029218

Subject(s)

Adenocarcinoma/genetics; Colorectal Neoplasms/genetics; Cytogenetic Analysis/methods; DNA Mutational Analysis/methods; Proto-Oncogene Proteins B-raf/genetics; Proto-Oncogene Proteins/genetics; ras Proteins/genetics; Adenocarcinoma/pathology; Adenocarcinoma/secondary; Aged; Aged, 80 and over; Antibodies, Monoclonal/therapeutic use; Antibodies, Monoclonal, Humanized; Biopsy, Fine-Needle/methods; Cetuximab; Colorectal Neoplasms/pathology; Colorectal Neoplasms/secondary; ErbB Receptors/genetics; ErbB Receptors/therapeutic use; Female; Humans; Male; Middle Aged; Mutation/genetics; Proto-Oncogene Proteins p21(ras)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Mutational Analysis / Colorectal Neoplasms / Adenocarcinoma / Proto-Oncogene Proteins / Ras Proteins / Cytogenetic Analysis / Proto-Oncogene Proteins B-raf Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Cytopathology Journal subject: PATOLOGIA Year: 2011 Document type: Article Affiliation country: Singapore Country of publication: United kingdom

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