The zinc-sensing transcription factor MTF-1 mediates zinc-induced epigenetic changes in chromatin of the mouse metallothionein-I promoter.

Okumura, Fumika; Li, Yong; Itoh, Norio; Nakanishi, Tsuyoshi; Isobe, Masakazu; Andrews, Glen K; Kimura, Tomoki

Okumura, Fumika; Li, Yong; Itoh, Norio; Nakanishi, Tsuyoshi; Isobe, Masakazu; Andrews, Glen K; Kimura, Tomoki.

Affiliation

Okumura F; Department of Toxicology, Faculty of Pharmaceutical Sciences, Setsunan University, Osaka 573-0101, Japan.

Biochim Biophys Acta ; 1809(1): 56-62, 2011 Jan.

Article in En | MEDLINE | ID: mdl-21035574

Subject(s)

Chromatin/metabolism; DNA-Binding Proteins/metabolism; Metallothionein/genetics; Promoter Regions, Genetic/genetics; Transcription Factors/metabolism; Acetylation/drug effects; Animals; Binding Sites/genetics; Blotting, Western; Cells, Cultured; Chromatin/genetics; Chromatin Immunoprecipitation; DNA-Binding Proteins/genetics; Embryo, Mammalian/cytology; Epigenesis, Genetic/drug effects; Epigenomics; Fibroblasts/cytology; Fibroblasts/metabolism; Histones/genetics; Histones/metabolism; Interleukin-6/pharmacology; Methylation/drug effects; Mice; Mice, Knockout; Mutation; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors/genetics; Transcriptional Activation/drug effects; Transcriptional Activation/genetics; Zinc/metabolism; Zinc/pharmacology; Transcription Factor MTF-1

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Chromatin / Promoter Regions, Genetic / DNA-Binding Proteins / Metallothionein Limits: Animals Language: En Journal: Biochim Biophys Acta Year: 2011 Document type: Article Affiliation country: Japan Country of publication: Netherlands

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google