In vitro and in vivo evaluation of ketotifen fumarate-loaded silicone hydrogel contact lenses for ocular drug delivery.

Xu, Jinku; Li, Xinsong; Sun, Fuqian

Xu, Jinku; Li, Xinsong; Sun, Fuqian.

Affiliation

Xu J; Biomaterials and Drug Delivery Laboratories, College of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189, PR China.

Drug Deliv ; 18(2): 150-8, 2011 Feb.

Article in En | MEDLINE | ID: mdl-21043996

Subject(s)

Contact Lenses; Drug Delivery Systems/methods; Hydrogel, Polyethylene Glycol Dimethacrylate/chemistry; Ketotifen/administration & dosage; Ophthalmic Solutions/administration & dosage; Silicones/chemistry; Animals; Drug Carriers/administration & dosage; Drug Carriers/chemical synthesis; Drug Carriers/chemistry; Drug Stability; Eye/drug effects; Eye/metabolism; Hydrogel, Polyethylene Glycol Dimethacrylate/administration & dosage; Hydrophobic and Hydrophilic Interactions; Ketotifen/chemistry; Ophthalmic Solutions/chemistry; Permeability; Rabbits; Silicones/administration & dosage; Tears/metabolism; Tensile Strength

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ophthalmic Solutions / Silicones / Drug Delivery Systems / Contact Lenses / Hydrogel, Polyethylene Glycol Dimethacrylate / Ketotifen Limits: Animals Language: En Journal: Drug Deliv Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2011 Document type: Article

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