Synergistic apoptosis induction in leukemic cells by miR-15a/16-1 and arsenic trioxide.

Gao, Shen-meng; Chen, Chiqi; Wu, Jianbo; Tan, Yanxia; Yu, Kang; Xing, Chong-Yun; Ye, Aifang; Yin, Lihui; Jiang, Lei

Gao, Shen-meng; Chen, Chiqi; Wu, Jianbo; Tan, Yanxia; Yu, Kang; Xing, Chong-Yun; Ye, Aifang; Yin, Lihui; Jiang, Lei.

Affiliation

Gao SM; Laboratory of Internal Medicine, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang 325000, China.

Biochem Biophys Res Commun ; 403(2): 203-8, 2010 Dec 10.

Article in En | MEDLINE | ID: mdl-21056550

Subject(s)

Antineoplastic Agents/therapeutic use; Apoptosis; Arsenicals/therapeutic use; Leukemia, Promyelocytic, Acute/drug therapy; MicroRNAs/therapeutic use; Oxides/therapeutic use; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Drug Synergism; Fusion Proteins, bcr-abl/metabolism; Humans; K562 Cells; Mitochondria/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxides / Arsenicals / Leukemia, Promyelocytic, Acute / Apoptosis / MicroRNAs / Antineoplastic Agents Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2010 Document type: Article Affiliation country: China Country of publication: United States

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