Cdc42-mediated MTOC polarization in dendritic cells controls targeted delivery of cytokines at the immune synapse.

Pulecio, Julian; Petrovic, Jelena; Prete, Francesca; Chiaruttini, Giulia; Lennon-Dumenil, Ana-Maria; Desdouets, Chantal; Gasman, Stephane; Burrone, Oscar R; Benvenuti, Federica

Pulecio, Julian; Petrovic, Jelena; Prete, Francesca; Chiaruttini, Giulia; Lennon-Dumenil, Ana-Maria; Desdouets, Chantal; Gasman, Stephane; Burrone, Oscar R; Benvenuti, Federica.

Affiliation

Pulecio J; International Centre for Genetic Engineering and Biotechnology, Padriciano 99, 34149, Trieste, Italy.

J Exp Med ; 207(12): 2719-32, 2010 Nov 22.

Article in En | MEDLINE | ID: mdl-21059854

Subject(s)

Dendritic Cells/physiology; Immunological Synapses/immunology; Interleukin-12/metabolism; Microtubule-Organizing Center/physiology; cdc42 GTP-Binding Protein/physiology; Animals; Cell Communication; Cell Polarity; Escherichia coli Infections/immunology; Female; Interferon-gamma/biosynthesis; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Signal Transduction; T-Lymphocytes/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Interleukin-12 / Cdc42 GTP-Binding Protein / Microtubule-Organizing Center / Immunological Synapses Limits: Animals Language: En Journal: J Exp Med Year: 2010 Document type: Article Affiliation country: Italy

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