Influence of antiplatelet drugs in the pathogenesis of experimental periodontitis and periodontal repair in rats.

Coimbra, Leila S; Rossa, Carlos; Guimarães, Morgana R; Gerlach, Raquel F; Muscará, Marcelo N; Spolidorio, Denise M P; Herrera, Bruno S; Spolidorio, Luis C

Coimbra, Leila S; Rossa, Carlos; Guimarães, Morgana R; Gerlach, Raquel F; Muscará, Marcelo N; Spolidorio, Denise M P; Herrera, Bruno S; Spolidorio, Luis C.

Affiliation

Coimbra LS; Department of Physiology and Pathology, Faculdade de Odontologia de Araraquara, UNESP, Universidade Estadual Paulista, Araraquara, SP, Brazil.

J Periodontol ; 82(5): 767-77, 2011 May.

Article in En | MEDLINE | ID: mdl-21073332

Subject(s)

Periodontitis/etiology; Periodontium/drug effects; Platelet Aggregation Inhibitors/therapeutic use; Alveolar Bone Loss/etiology; Alveolar Bone Loss/pathology; Alveolar Bone Loss/prevention & control; Animals; Aspirin/therapeutic use; Blood Platelets/drug effects; Bone Density/drug effects; Bone Regeneration/drug effects; Clopidogrel; Inflammation Mediators/analysis; Intercellular Signaling Peptides and Proteins/analysis; Interleukin-6/analysis; Leukocytes/drug effects; Male; Mandibular Diseases/etiology; Mandibular Diseases/pathology; Mandibular Diseases/prevention & control; Periodontal Attachment Loss/etiology; Periodontal Attachment Loss/pathology; Periodontal Attachment Loss/prevention & control; Periodontitis/pathology; Periodontitis/prevention & control; Periodontium/pathology; Platelet Activation/drug effects; Random Allocation; Rats; Rats, Sprague-Dawley; Thromboxane A2/analysis; Ticlopidine/analogs & derivatives; Ticlopidine/therapeutic use; Time Factors; Tumor Necrosis Factor-alpha/drug effects; Wound Healing/drug effects; X-Ray Microtomography

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Periodontitis / Periodontium / Platelet Aggregation Inhibitors Type of study: Etiology_studies Language: En Journal: J Periodontol Year: 2011 Document type: Article Affiliation country: Brazil Country of publication: United States

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