Transmural differences in respiratory capacity across the rat left ventricle in health, aging, and streptozotocin-induced diabetes mellitus: evidence that mitochondrial dysfunction begins in the subepicardium.

MacDonald, J R; Oellermann, M; Rynbeck, S; Chang, G; Ruggiero, K; Cooper, G J S; Hickey, A J R

MacDonald, J R; Oellermann, M; Rynbeck, S; Chang, G; Ruggiero, K; Cooper, G J S; Hickey, A J R.

Affiliation

MacDonald JR; University of Auckland, School of Biological Sciences, Private Bag 92019, Auckland Mail Centre, Auckland 1142, New Zealand.

Am J Physiol Cell Physiol ; 300(2): C246-55, 2011 Feb.

Article in En | MEDLINE | ID: mdl-21084644

Subject(s)

Aging/physiology; Diabetes Mellitus, Experimental/physiopathology; Diabetic Cardiomyopathies/physiopathology; Mitochondria, Heart/physiology; Mitochondrial Diseases/physiopathology; Oxygen Consumption/physiology; Pericardium/physiopathology; Ventricular Dysfunction, Left/physiopathology; Animals; Diabetes Mellitus, Experimental/diagnostic imaging; Diabetic Cardiomyopathies/diagnostic imaging; Echocardiography, Doppler; Heart Rate/physiology; Male; Mitochondria, Heart/diagnostic imaging; Mitochondria, Heart/ultrastructure; Mitochondrial Diseases/diagnostic imaging; Myocardial Contraction; Pericardium/diagnostic imaging; Pericardium/ultrastructure; Rats; Rats, Wistar; Ventricular Dysfunction, Left/diagnostic imaging

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxygen Consumption / Pericardium / Aging / Ventricular Dysfunction, Left / Mitochondrial Diseases / Diabetes Mellitus, Experimental / Diabetic Cardiomyopathies / Mitochondria, Heart Limits: Animals Language: En Journal: Am J Physiol Cell Physiol Journal subject: FISIOLOGIA Year: 2011 Document type: Article Affiliation country: New Zealand Country of publication: United States

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