Centchroman inhibits proliferation of head and neck cancer cells through the modulation of PI3K/mTOR pathway.

Srivastava, Vikas Kumar; Gara, Rishi Kumar; Bhatt, M L B; Sahu, D P; Mishra, Durga Prasad

Srivastava, Vikas Kumar; Gara, Rishi Kumar; Bhatt, M L B; Sahu, D P; Mishra, Durga Prasad.

Affiliation

Srivastava VK; Department of Radiotherapy, C.S.M. Medical University, Lucknow, Uttar Pradesh 226003, India.

Biochem Biophys Res Commun ; 404(1): 40-5, 2011 Jan 07.

Article in En | MEDLINE | ID: mdl-21094138

Subject(s)

Carcinoma, Squamous Cell/enzymology; Cell Proliferation/drug effects; Centchroman/pharmacology; Estrogen Antagonists/pharmacology; Head and Neck Neoplasms/enzymology; Phosphoinositide-3 Kinase Inhibitors; TOR Serine-Threonine Kinases/antagonists & inhibitors; Cell Cycle/drug effects; Cell Line, Tumor; DNA Damage/drug effects; Humans; STAT3 Transcription Factor/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Centchroman / Cell Proliferation / Estrogen Antagonists / TOR Serine-Threonine Kinases / Phosphoinositide-3 Kinase Inhibitors / Head and Neck Neoplasms Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2011 Document type: Article Affiliation country: India Country of publication: United States

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