[Transforming of the drug resistance plasmid from Staphylococcus aureus into Escherichia coli].

OBJECTIVE: To discuss the possible mechanism of drug resistance transmission between Staphylococcus and Escherichia coli. METHODS: The chloramphenicol resistance plasmid of Staphylococcus aureus was extracted to transform the sensitive Escherichia coli, and the drug-resistant Escherichia coli were screened by drug sensitivity test. RESULTS: The drug-resistant Escherichia coli were successfully obtained. CONCLUSION: Staphylococcus may have a natural shuttle plasmid of drug resistance, which can transform Escherichia coli under specific conditions.