Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors, and Ca channel antagonists.

Tomassoli, Isabelle; Ismaili, Lhassane; Pudlo, Marc; de Los Ríos, Cristóbal; Soriano, Elena; Colmena, Inés; Gandía, Luis; Rivas, Luis; Samadi, Abdelouahid; Marco-Contelles, José; Refouvelet, Bernard

Tomassoli, Isabelle; Ismaili, Lhassane; Pudlo, Marc; de Los Ríos, Cristóbal; Soriano, Elena; Colmena, Inés; Gandía, Luis; Rivas, Luis; Samadi, Abdelouahid; Marco-Contelles, José; Refouvelet, Bernard.

Affiliation

Tomassoli I; Laboratoire de Chimie Thérapeutique Equipe 2SBP EA4267, 4 place saint Jacques 25030 Besancon Cedex, France. isabelle.tomassoli@edu.univ-fcomte.fr

Eur J Med Chem ; 46(1): 1-10, 2011 Jan.

Article in En | MEDLINE | ID: mdl-21111515

Subject(s)

Calcium Channels/metabolism; Cholinesterases/metabolism; Hydrazines/chemical synthesis; Hydrazines/pharmacology; Models, Molecular; Quinolines/chemical synthesis; Quinolines/pharmacology; Animals; Calcium Channel Blockers/chemical synthesis; Calcium Channel Blockers/chemistry; Calcium Channel Blockers/pharmacology; Calcium Channels/chemistry; Catalytic Domain; Cattle; Cholinesterase Inhibitors/chemical synthesis; Cholinesterase Inhibitors/chemistry; Cholinesterase Inhibitors/pharmacology; Cholinesterases/chemistry; Drug Design; Electrophorus; Hydrazines/chemistry; Quinolines/chemistry

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Calcium Channels / Models, Molecular / Cholinesterases / Hydrazines Limits: Animals Language: En Journal: Eur J Med Chem Year: 2011 Document type: Article Affiliation country: France Country of publication: France

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google