Development and characterization of high affinity leptins and leptin antagonists.

Shpilman, Michal; Niv-Spector, Leonora; Katz, Meirav; Varol, Chen; Solomon, Gili; Ayalon-Soffer, Michal; Boder, Eric; Halpern, Zamir; Elinav, Eran; Gertler, Arieh

Shpilman, Michal; Niv-Spector, Leonora; Katz, Meirav; Varol, Chen; Solomon, Gili; Ayalon-Soffer, Michal; Boder, Eric; Halpern, Zamir; Elinav, Eran; Gertler, Arieh.

Affiliation

Shpilman M; Robert H Smith Faculty of Agriculture, Food and Environment, Hebrew University, Rehovot 76100, Israel.

J Biol Chem ; 286(6): 4429-42, 2011 Feb 11.

Article in En | MEDLINE | ID: mdl-21119198

Subject(s)

Amino Acid Substitution; Body Weight/drug effects; Eating/drug effects; Leptin/analogs & derivatives; Mutation, Missense; Polyethylene Glycols; Animals; HEK293 Cells; Humans; Leptin/antagonists & inhibitors; Leptin/chemistry; Leptin/genetics; Leptin/metabolism; Leptin/pharmacology; Male; Mice; Mutagenesis; Polyethylene Glycols/chemistry; Polyethylene Glycols/metabolism; Polyethylene Glycols/pharmacology; Protein Binding; Receptors, Leptin/genetics; Receptors, Leptin/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Body Weight / Amino Acid Substitution / Mutation, Missense / Leptin / Eating Limits: Animals / Humans / Male Language: En Journal: J Biol Chem Year: 2011 Document type: Article Affiliation country: Israel Country of publication: United States

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