Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception.

Kumar, Lalit; Sarswat, Amit; Lal, Nand; Jain, Ashish; Kumar, Sumit; Kiran Kumar, S T V S; Maikhuri, Jagdamba P; Pandey, Atindra K; Shukla, Praveen K; Gupta, Gopal; Sharma, Vishnu L

Kumar, Lalit; Sarswat, Amit; Lal, Nand; Jain, Ashish; Kumar, Sumit; Kiran Kumar, S T V S; Maikhuri, Jagdamba P; Pandey, Atindra K; Shukla, Praveen K; Gupta, Gopal; Sharma, Vishnu L.

Affiliation

Kumar L; Division of Medicinal and Process Chemistry, Central Drug Research Institute, CSIR, Lucknow 226 001, India.

Bioorg Med Chem Lett ; 21(1): 176-81, 2011 Jan 01.

Article in En | MEDLINE | ID: mdl-21130651

Subject(s)

Anti-Infective Agents/chemical synthesis; Antifungal Agents/chemical synthesis; Contraceptive Agents, Female/chemical synthesis; Propane/chemistry; Spermatocidal Agents/chemical synthesis; Anti-Infective Agents/chemistry; Anti-Infective Agents/toxicity; Antifungal Agents/chemistry; Antifungal Agents/toxicity; Contraceptive Agents, Female/chemistry; Contraceptive Agents, Female/toxicity; Drug Design; Female; HeLa Cells; Humans; Lactobacillus/drug effects; Propane/chemical synthesis; Propane/toxicity; Spermatocidal Agents/chemistry; Spermatocidal Agents/toxicity; Structure-Activity Relationship; Trichomonas vaginalis/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propane / Spermatocidal Agents / Contraceptive Agents, Female / Anti-Infective Agents / Antifungal Agents Limits: Female / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Document type: Article Affiliation country: India Country of publication: United kingdom

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