Altered dipeptidyl peptidase-4 activity during the progression of hyperinsulinemic obesity and islet atrophy in spontaneously late-stage type 2 diabetic rats.

Kirino, Yasushi; Sato, Youichi; Kamimoto, Takayuki; Kawazoe, Kazuyoshi; Minakuchi, Kazuo

Kirino, Yasushi; Sato, Youichi; Kamimoto, Takayuki; Kawazoe, Kazuyoshi; Minakuchi, Kazuo.

Affiliation

Kirino Y; Department of Human Genetics and Public Health, Inst. of Health Biosciences, Univ. of Tokushima Graduate School, Japan.

Am J Physiol Endocrinol Metab ; 300(2): E372-9, 2011 Feb.

Article in En | MEDLINE | ID: mdl-21139073

Subject(s)

Diabetes Mellitus, Type 2/enzymology; Dipeptidyl Peptidase 4/metabolism; Hyperinsulinism/enzymology; Islets of Langerhans/pathology; Obesity/enzymology; Animals; Area Under Curve; Atrophy; Blood Glucose/metabolism; Body Weight/physiology; Disease Progression; Food Deprivation; Glucose Tolerance Test; Immunohistochemistry; Insulin/blood; Insulin/metabolism; Male; Organ Size/physiology; Proteinuria/metabolism; Rats; Rats, Inbred OLETF; Reverse Transcriptase Polymerase Chain Reaction; Satiation

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Islets of Langerhans / Dipeptidyl Peptidase 4 / Diabetes Mellitus, Type 2 / Hyperinsulinism / Obesity Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Physiol Endocrinol Metab Journal subject: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Year: 2011 Document type: Article Affiliation country: Japan Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google