Persistent pro-inflammatory cytokines following the initiation of pegylated IFN therapy in hepatitis C infection is associated with treatment-induced depression.

Krueger, C; Hawkins, K; Wong, S; Enns, M W; Minuk, G; Rempel, J D

Krueger, C; Hawkins, K; Wong, S; Enns, M W; Minuk, G; Rempel, J D.

Affiliation

Krueger C; Section of Hepatology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada.

J Viral Hepat ; 18(7): e284-91, 2011 Jul.

Article in En | MEDLINE | ID: mdl-21143344

Subject(s)

Antiviral Agents/adverse effects; Cytokines/biosynthesis; Depression/chemically induced; Hepatitis C/drug therapy; Interferon-alpha/adverse effects; Interferons/adverse effects; Polyethylene Glycols/adverse effects; Adult; Antiviral Agents/therapeutic use; Cytokines/genetics; Female; Humans; Interferon alpha-2; Interferon-alpha/therapeutic use; Interferon-beta; Interferons/therapeutic use; Male; Middle Aged; Polyethylene Glycols/therapeutic use; Polymerase Chain Reaction; RNA, Messenger/analysis; RNA, Messenger/biosynthesis; Recombinant Proteins/adverse effects; Recombinant Proteins/therapeutic use; Surveys and Questionnaires

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Polyethylene Glycols / Cytokines / Interferons / Interferon-alpha / Hepatitis C / Depression Type of study: Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Viral Hepat Journal subject: GASTROENTEROLOGIA Year: 2011 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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