Biosynthesis of the spiroacetal suite in Bactrocera tryoni.
Chembiochem
; 12(1): 155-72, 2011 Jan 03.
Article
in En
| MEDLINE
| ID: mdl-21154610
ABSTRACT
In pursuit of a more environmentally benign method of controlling the highly pestiferous Queensland fruit fly, Bactrocera tryoni, the biosynthesis of the minor components in the suite of spiroacetals released by females has been investigated. This follows on the biosynthetic definition of the pathway to the major component, (E,E)-1. The origins of the C(12) and C(13) spiroacetals (E,E)-2 and (E,E)-3, respectively, have been investigated by the administration of over 30 deuterated potential precursors. Analysis of the relative incorporation levels and identification of some of the exceptionally minor spiroacetals that were biosynthesised established that B. tryoni processes fatty acids to 2,6-dioxygenated precursors by a modified ß-oxidation pathway, with a suite of putative cytochromes P450 employed in the crucial oxidative steps, prior to cyclisation of the proposed ketodiol.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spiro Compounds
/
Tephritidae
Limits:
Animals
Language:
En
Journal:
Chembiochem
Journal subject:
BIOQUIMICA
Year:
2011
Document type:
Article
Affiliation country:
Australia