Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.
J Am Chem Soc
; 133(4): 976-85, 2011 Feb 02.
Article
in En
| MEDLINE
| ID: mdl-21175203
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tacrolimus
/
Sequence Deletion
/
Polyketide Synthases
/
Malonyl Coenzyme A
Language:
En
Journal:
J Am Chem Soc
Year:
2011
Document type:
Article