Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors.

Zou, Junhuang; Luo, Ling; Shen, Zuolian; Chiodo, Vince A; Ambati, Balamurali K; Hauswirth, William W; Yang, Jun

Zou, Junhuang; Luo, Ling; Shen, Zuolian; Chiodo, Vince A; Ambati, Balamurali K; Hauswirth, William W; Yang, Jun.

Affiliation

Zou J; Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA.

Invest Ophthalmol Vis Sci ; 52(5): 2343-51, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21212183

Subject(s)

Extracellular Matrix Proteins/genetics; Gene Expression Regulation/physiology; Genetic Vectors; Membrane Proteins/genetics; Photoreceptor Cells, Vertebrate/metabolism; Animals; Animals, Newborn; Blotting, Western; Dependovirus/genetics; Electroretinography; Extracellular Matrix Proteins/metabolism; Fluorescent Antibody Technique, Indirect; G-Protein-Coupled Receptor Kinase 1/genetics; Gene Deletion; Membrane Proteins/metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Microscopy, Immunoelectron; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, G-Protein-Coupled/genetics; Receptors, G-Protein-Coupled/metabolism; Transgenes; Usher Syndromes/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Extracellular Matrix Proteins / Photoreceptor Cells, Vertebrate / Genetic Vectors / Membrane Proteins Limits: Animals Language: En Journal: Invest Ophthalmol Vis Sci Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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