Noninvasive magnetic resonance imaging detection of cerebral amyloid angiopathy-related microvascular alterations using superparamagnetic iron oxide particles in APP transgenic mouse models of Alzheimer's disease: application to passive Abeta immunotherapy.

Beckmann, Nicolau; Gérard, Christelle; Abramowski, Dorothée; Cannet, Catherine; Staufenbiel, Matthias

Beckmann, Nicolau; Gérard, Christelle; Abramowski, Dorothée; Cannet, Catherine; Staufenbiel, Matthias.

Affiliation

Beckmann N; Global Imaging Group, Novartis Institutes for BioMedical Research, CH-4056 Basel, Switzerland. nicolau.beckmann@novartis.com

J Neurosci ; 31(3): 1023-31, 2011 Jan 19.

Article in En | MEDLINE | ID: mdl-21248127

Subject(s)

Alzheimer Disease/pathology; Amyloid beta-Protein Precursor/genetics; Cerebral Amyloid Angiopathy/pathology; Cerebral Cortex/pathology; Magnetite Nanoparticles; Alzheimer Disease/genetics; Analysis of Variance; Animals; Cerebral Amyloid Angiopathy/genetics; Disease Models, Animal; Female; Immunization, Passive; Magnetic Resonance Imaging; Male; Mice; Mice, Transgenic; Statistics, Nonparametric

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cerebral Cortex / Cerebral Amyloid Angiopathy / Amyloid beta-Protein Precursor / Magnetite Nanoparticles / Alzheimer Disease Type of study: Diagnostic_studies / Observational_studies / Risk_factors_studies Limits: Animals Language: En Journal: J Neurosci Year: 2011 Document type: Article Affiliation country: Switzerland Country of publication: United States

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