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Laevigatbenzoate from Croton laevigatus Vahl.
Zou, Guo-An; Zhang, Hong-Wu; Aisa, Haji Akber; Yang, Jun-Shan; Peng, Chao-Zhong; Zou, Zhong-Mei.
Affiliation
  • Zou GA; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, People's Republic of China.
J Nat Med ; 65(2): 391-4, 2011 Apr.
Article in En | MEDLINE | ID: mdl-21253863
ABSTRACT
A new trans-clerodane diterpenoid, laevigatbenzoate (1), was isolated from the leaves of Croton laevigatus Vahl. Its structure was established on the basis of spectroscopic analysis, and the absolute configuration was determined by application of the CD excitation chirality method. This compound showed weak cytotoxicity against HeLa cells, with an IC(50) value of 45.4 µM.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diterpenes / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: J Nat Med Journal subject: TERAPIAS COMPLEMENTARES Year: 2011 Document type: Article Publication country: JAPAN / JAPON / JAPÃO / JP
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diterpenes / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: J Nat Med Journal subject: TERAPIAS COMPLEMENTARES Year: 2011 Document type: Article Publication country: JAPAN / JAPON / JAPÃO / JP