Laevigatbenzoate from Croton laevigatus Vahl.
J Nat Med
; 65(2): 391-4, 2011 Apr.
Article
in En
| MEDLINE
| ID: mdl-21253863
ABSTRACT
A new trans-clerodane diterpenoid, laevigatbenzoate (1), was isolated from the leaves of Croton laevigatus Vahl. Its structure was established on the basis of spectroscopic analysis, and the absolute configuration was determined by application of the CD excitation chirality method. This compound showed weak cytotoxicity against HeLa cells, with an IC(50) value of 45.4 µM.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Diterpenes
/
Antineoplastic Agents, Phytogenic
Limits:
Humans
Language:
En
Journal:
J Nat Med
Journal subject:
TERAPIAS COMPLEMENTARES
Year:
2011
Document type:
Article
Publication country:
JAPAN
/
JAPON
/
JAPÃO
/
JP