Vitronectin accumulates in the interstitium but minimally impacts fibrogenesis in experimental chronic kidney disease.

López-Guisa, Jesús M; Rassa, Allen C; Cai, Xiaohe; Collins, Sarah J; Eddy, Allison A

López-Guisa, Jesús M; Rassa, Allen C; Cai, Xiaohe; Collins, Sarah J; Eddy, Allison A.

Affiliation

López-Guisa JM; Seattle Children's Research Institute, Department of Pediatrics, University of Washington, USA.

Am J Physiol Renal Physiol ; 300(5): F1244-54, 2011 May.

Article in En | MEDLINE | ID: mdl-21270094

Subject(s)

Kidney Diseases/etiology; Kidney/metabolism; Myofibroblasts/metabolism; Ureteral Obstruction/complications; Vimentin/metabolism; Animals; Chronic Disease; Disease Models, Animal; Fibrosis; Genotype; Integrin alphaVbeta3/metabolism; Kidney/pathology; Kidney Diseases/genetics; Kidney Diseases/metabolism; Kidney Diseases/pathology; Macrophages/metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts/pathology; Phenotype; Plasminogen Activator Inhibitor 1/metabolism; Plasminogen Activators/metabolism; RNA, Messenger/metabolism; Receptors, Urokinase Plasminogen Activator/metabolism; Time Factors; Up-Regulation; Ureteral Obstruction/genetics; Ureteral Obstruction/metabolism; Ureteral Obstruction/pathology; Vimentin/deficiency; Vimentin/genetics

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ureteral Obstruction / Vimentin / Myofibroblasts / Kidney / Kidney Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Physiol Renal Physiol Journal subject: FISIOLOGIA / NEFROLOGIA Year: 2011 Document type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google