The role of C-reactive protein as a risk predictor of coronary atherosclerosis: implications from the JUPITER trial.
Curr Atheroscler Rep
; 13(2): 154-61, 2011 Apr.
Article
in En
| MEDLINE
| ID: mdl-21274757
ABSTRACT
Much controversy surrounds the use of high-sensitivity C-reactive protein (hs-CRP) as a marker of cardiovascular (CV) risk. Although data regarding the association of hs-CRP with CV disease is extensive and consistent, its role in clinical practice remains unclear. The American Heart Association (AHA) recently published a scientific statement regarding criteria for evaluation of novel markers of CV risk. This article provides a comprehensive review of data regarding hs-CRP as a risk marker for CV disease in the context of these AHA criteria. The impact of the JUPITER trial on the utility of hs-CRP as a risk marker is emphasized. The review concludes with an evidence-based statement regarding the current role of hs-CRP in CV risk prediction.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pyrimidines
/
Sulfonamides
/
Coronary Artery Disease
/
C-Reactive Protein
/
Fluorobenzenes
Type of study:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
Curr Atheroscler Rep
Journal subject:
ANGIOLOGIA
Year:
2011
Document type:
Article
Affiliation country:
United States