Excessive hepatomegaly of mice with hepatocyte-targeted elimination of integrin linked kinase following treatment with 1,4-bis [2-(3,5-dichaloropyridyloxy)] benzene.

Donthamsetty, Shashikiran; Bhave, Vishakha S; Kliment, Corrine S; Bowen, William C; Mars, Wendy M; Bell, Aaron W; Stewart, Rachel E; Orr, Anne; Wu, Chuanyue; Michalopoulos, George K

Donthamsetty, Shashikiran; Bhave, Vishakha S; Kliment, Corrine S; Bowen, William C; Mars, Wendy M; Bell, Aaron W; Stewart, Rachel E; Orr, Anne; Wu, Chuanyue; Michalopoulos, George K.

Affiliation

Donthamsetty S; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

Hepatology ; 53(2): 587-95, 2011 Feb.

Article in En | MEDLINE | ID: mdl-21274879

Subject(s)

Hepatocytes/metabolism; Hepatocytes/pathology; Hepatomegaly/chemically induced; Hepatomegaly/pathology; Protein Serine-Threonine Kinases/metabolism; Pyridines/adverse effects; Animals; Body Weight/physiology; Cell Cycle/physiology; Cell Proliferation; Disease Models, Animal; Extracellular Matrix/physiology; Hepatomegaly/metabolism; Mice; Mice, Knockout; Organ Size/physiology; Protein Serine-Threonine Kinases/genetics; Proto-Oncogene Proteins c-myc/metabolism; Signal Transduction/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Protein Serine-Threonine Kinases / Hepatocytes / Hepatomegaly Limits: Animals Language: En Journal: Hepatology Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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