Methotrexate is highly potent against pyrimethamine-resistant Plasmodium vivax.

Imwong, Mallika; Russell, Bruce; Suwanarusk, Rossarin; Nzila, Alexis; Leimanis, Mara L; Sriprawat, Kanlaya; Kaewpongsri, Supaporn; Phyo, Aung Pyae; Snounou, Georges; Nosten, Francois; Renia, Laurent

Imwong, Mallika; Russell, Bruce; Suwanarusk, Rossarin; Nzila, Alexis; Leimanis, Mara L; Sriprawat, Kanlaya; Kaewpongsri, Supaporn; Phyo, Aung Pyae; Snounou, Georges; Nosten, Francois; Renia, Laurent.

Affiliation

Imwong M; Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok.

J Infect Dis ; 203(2): 207-10, 2011 Jan 15.

Article in En | MEDLINE | ID: mdl-21288820

Subject(s)

Antimalarials/pharmacology; Methotrexate/pharmacology; Plasmodium vivax/drug effects; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Vivax/parasitology; Mutation, Missense; Plasmodium vivax/isolation & purification; Protozoan Proteins/genetics; Pyrimethamine/pharmacology; Tetrahydrofolate Dehydrogenase/genetics

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium vivax / Methotrexate / Antimalarials Limits: Humans Language: En Journal: J Infect Dis Year: 2011 Document type: Article Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google