Electrospun diclofenac sodium loaded Eudragit® L 100-55 nanofibers for colon-targeted drug delivery.

Shen, Xiaxia; Yu, Dengguang; Zhu, Limin; Branford-White, Christopher; White, Kenneth; Chatterton, Nicholas P

Shen, Xiaxia; Yu, Dengguang; Zhu, Limin; Branford-White, Christopher; White, Kenneth; Chatterton, Nicholas P.

Affiliation

Shen X; College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, PR China.

Int J Pharm ; 408(1-2): 200-7, 2011 Apr 15.

Article in En | MEDLINE | ID: mdl-21291969

Subject(s)

Acrylic Resins/chemistry; Anti-Inflammatory Agents, Non-Steroidal/chemistry; Colon/metabolism; Diclofenac/chemistry; Drug Carriers/chemistry; Nanofibers/chemistry; Technology, Pharmaceutical/methods; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Anti-Inflammatory Agents, Non-Steroidal/pharmacokinetics; Calorimetry, Differential Scanning; Diclofenac/administration & dosage; Diclofenac/pharmacokinetics; Electrochemical Techniques; Hydrogen Bonding; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Particle Size; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Surface Properties; Thermography

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acrylic Resins / Drug Carriers / Anti-Inflammatory Agents, Non-Steroidal / Diclofenac / Technology, Pharmaceutical / Colon / Nanofibers Language: En Journal: Int J Pharm Year: 2011 Document type: Article Country of publication: Netherlands

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