SBML-PET-MPI: a parallel parameter estimation tool for Systems Biology Markup Language based models.
Bioinformatics
; 27(7): 1028-9, 2011 Apr 01.
Article
in En
| MEDLINE
| ID: mdl-21303862
ABSTRACT
UNLABELLED Parameter estimation is crucial for the modeling and dynamic analysis of biological systems. However, implementing parameter estimation is time consuming and computationally demanding. Here, we introduced a parallel parameter estimation tool for Systems Biology Markup Language (SBML)-based models (SBML-PET-MPI). SBML-PET-MPI allows the user to perform parameter estimation and parameter uncertainty analysis by collectively fitting multiple experimental datasets. The tool is developed and parallelized using the message passing interface (MPI) protocol, which provides good scalability with the number of processors. AVAILABILITY:
SBML-PET-MPI is freely available for non-commercial use at http//www.bioss.uni-freiburg.de/cms/sbml-pet-mpi.html or http//sites.google.com/site/sbmlpetmpi/.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Software
/
Systems Biology
/
Models, Biological
Language:
En
Journal:
Bioinformatics
Journal subject:
INFORMATICA MEDICA
Year:
2011
Document type:
Article
Affiliation country:
Germany