Marginal iodide deficiency and thyroid function: dose-response analysis for quantitative pharmacokinetic modeling.

Gilbert, M E; McLanahan, E D; Hedge, J; Crofton, K M; Fisher, J W; Valentín-Blasini, L; Blount, B C

Gilbert, M E; McLanahan, E D; Hedge, J; Crofton, K M; Fisher, J W; Valentín-Blasini, L; Blount, B C.

Affiliation

Gilbert ME; Toxicity Assessment Division (MD-B105-05), National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, 109 TW Alexander Drive, Research Triangle Park, NC 27711, USA. gilbert.mary@epa.gov

Toxicology ; 283(1): 41-8, 2011 Apr 28.

Article in En | MEDLINE | ID: mdl-21315791

Subject(s)

Iodine/deficiency; Thyroid Gland/metabolism; Thyrotropin/metabolism; Thyroxine/metabolism; Triiodothyronine/metabolism; Animals; Body Weight/physiology; Dose-Response Relationship, Drug; Eating/physiology; Female; Iodine/administration & dosage; Iodine/pharmacokinetics; Iodine/urine; Models, Animal; Models, Biological; Organ Size/physiology; Rats; Rats, Long-Evans; Thyroid Gland/chemistry; Thyrotropin/blood; Thyroxine/blood; Triiodothyronine/blood

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Gland / Thyroxine / Triiodothyronine / Thyrotropin / Iodine Type of study: Prognostic_studies Limits: Animals Language: En Journal: Toxicology Year: 2011 Document type: Article Affiliation country: United States

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