Toxicity of neurons treated with herbicides and neuroprotection by mitochondria-targeted antioxidant SS31.

Reddy, Tejaswini P; Manczak, Maria; Calkins, Marcus J; Mao, Peizhong; Reddy, Arubala P; Shirendeb, Ulziibat; Park, Byung; Reddy, P Hemachandra

Reddy, Tejaswini P; Manczak, Maria; Calkins, Marcus J; Mao, Peizhong; Reddy, Arubala P; Shirendeb, Ulziibat; Park, Byung; Reddy, P Hemachandra.

Affiliation

Reddy TP; Neurogenetics Laboratory, Division of Neuroscience, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, OR 97006, USA. tejaswinireddy99@gmail.com

Int J Environ Res Public Health ; 8(1): 203-21, 2011 01.

Article in En | MEDLINE | ID: mdl-21318024

Subject(s)

Antioxidants/physiology; Glycolates/toxicity; Herbicides/toxicity; Neurons/drug effects; Oligopeptides/physiology; Picloram/toxicity; Animals; Antioxidants/administration & dosage; Cell Line, Tumor; Cell Survival; Electron Transport Chain Complex Proteins/biosynthesis; Forkhead Box Protein O1; Forkhead Transcription Factors/biosynthesis; Mice; Mice, Inbred C57BL; Neuroblastoma; Neurons/pathology; Neurons/physiology; Oligopeptides/administration & dosage; Oxidative Stress; Peroxiredoxins/biosynthesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; RNA/analysis; RNA, Messenger/biosynthesis; RNA, Messenger/drug effects; Receptors, N-Methyl-D-Aspartate/biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators/biosynthesis; Transcription Factors; Transcription, Genetic

Key words

Mitochondria-targeted antioxidant; Picloram; Szeto-Schiller peptide 31; Triclopyr; electron transport chain; herbicides; mouse neuroblastoma cells; mouse primary hippocampal neurons; oxidative stress

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Picloram / Glycolates / Herbicides / Neurons / Antioxidants Limits: Animals Language: En Journal: Int J Environ Res Public Health Year: 2011 Document type: Article Affiliation country: United States Country of publication: Switzerland

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