A tryptophan-rich motif in the human parainfluenza virus type 2 V protein is critical for the blockade of toll-like receptor 7 (TLR7)- and TLR9-dependent signaling.

Kitagawa, Yoshinori; Yamaguchi, Mayu; Zhou, Min; Komatsu, Takayuki; Nishio, Machiko; Sugiyama, Tsuyoshi; Takeuchi, Kenji; Itoh, Masae; Gotoh, Bin

Kitagawa, Yoshinori; Yamaguchi, Mayu; Zhou, Min; Komatsu, Takayuki; Nishio, Machiko; Sugiyama, Tsuyoshi; Takeuchi, Kenji; Itoh, Masae; Gotoh, Bin.

Affiliation

Kitagawa Y; Division of Microbiology and Infectious Diseases, Department of Pathology, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga 520-2192, Japan.

J Virol ; 85(9): 4606-11, 2011 May.

Article in En | MEDLINE | ID: mdl-21345944

Subject(s)

Dendritic Cells/immunology; Dendritic Cells/virology; Parainfluenza Virus 2, Human/pathogenicity; Signal Transduction; Toll-Like Receptor 7/antagonists & inhibitors; Toll-Like Receptor 9/antagonists & inhibitors; Viral Proteins/metabolism; Humans

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Dendritic Cells / Signal Transduction / Parainfluenza Virus 2, Human / Toll-Like Receptor 9 / Toll-Like Receptor 7 Limits: Humans Language: En Journal: J Virol Year: 2011 Document type: Article Affiliation country: Japan Country of publication: United States

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