Reproducibility of fMRI activations during a story listening task in patients with schizophrenia.
Schizophr Res
; 128(1-3): 98-101, 2011 May.
Article
in En
| MEDLINE
| ID: mdl-21349690
ABSTRACT
A prerequisite to longitudinal fMRI studies in schizophrenia is the knowledge on fMRI signal reliability in schizophrenia patients. We assessed the reproducibility of activations elicited by two fMRI sessions, which were 21 months apart, of a story listening paradigm in 10 schizophrenia patients and 10 healthy subjects. In both groups, we observed a high degree of spatial overlap of activation maps as well as a good reproducibility of signal variations assessed on a voxel-wise basis in temporal areas underlying early stages of language processing. Task performance, assessed through a comprehension questionnaire, had no impact on the activation reproducibility.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Schizophrenia
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Schizophrenic Psychology
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Brain
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Brain Mapping
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Comprehension
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Language
Type of study:
Observational_studies
Limits:
Adult
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Female
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Humans
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Male
/
Middle aged
Language:
En
Journal:
Schizophr Res
Journal subject:
PSIQUIATRIA
Year:
2011
Document type:
Article
Affiliation country:
France